Research has suggested that nicotine found in smoking cessation therapies could increase the risk of mouth cancer. Although this was previously not believed to be the case, the new findings are alarming. Nicotine and tobacco products containing nicotine are both known carcinogens, so the use of these products could increase the risk of mouth cancer. The research has been published in the international online science journal PLoS ONE. The study was funded by the Medical Research Council and other sources including the Institute of Dentistry, Barts, and Queen Mary Universities in London.
Smoking causes periodontal disease
Smoking is a known risk factor for periodontal disease, as well as cardiovascular disease. However, a commentator's view of this relationship is misleading and ignores the pathogenic role of bacteria. Although many studies suggest that smoking contributes to the development of periodontal disease, the vast majority point to the contribution of environmental risk factors.
Smoking weakens the immune system, making it more vulnerable to infections from harmful bacteria. It also reduces circulation, which is crucial to the gum tissue. Poor circulation is a risk factor for gum recession. Smoking is also a barrier to healing. As a result, periodontal treatment for smoking patients may not be as effective as for those with normal gum health.
Nicotine replacement therapy causes oral cancer
Recent research suggests that the nicotine found in nicotine replacement therapy increases the risk of mouth cancer. The research is published in the international online science journal PLoS ONE. The researchers examined the effect of different tobacco substances on oral cells and found that nicotine increased the expression of the FOXM1 gene. This gene is associated with the development of several types of cancer, including oral cancer.
The researchers used laboratory-grown mouth cells to study the effects of nicotine on these cells. They found that nicotine triggers the gene FOXM1 which speeds up the conversion of normal cells into cancerous ones. Although nicotine is not a known carcinogen, it is highly addictive and can be toxic in high doses. As a result, it is not recommended for long-term use.
Nicotine gum
Some research has suggested that using nicotine gum and other tobacco replacement products increases the risk of developing mouth cancer. While nicotine is not particularly carcinogenic, it may interact with a gene that increases the risk of cancer. This mutation is found in many types of tumors. To assess this risk further, researchers examined the levels of nicotine and the level of FOXM1 gene activity in cancerous and normal mouth tissue.
The Lung Health Study 3 followed participants for five years from their fifth annual visit until December 2001. At the end of the study, the researchers classified the cancers diagnosed into three categories: lung cancer, gastrointestinal tract cancer, and all cancers. The study primarily focused on the latter two categories because of the belief that nicotine in gum might provide exposure to the gastrointestinal tract.
Smokeless tobacco causes oral cancer
Smokeless tobacco contains over 30 cancer-causing chemicals, including nicotine, which is very addictive. These chemicals are absorbed into oral tissues, where they cause mutations in DNA. Over time, the damaged cells grow and eventually form a tumor. The disease is debilitating and often causes facial deformities and difficulty eating.
Smokeless tobacco is mostly used in Southeast Asia, which has the highest rate of oral cancer in the world. It is most popular in India and Bangladesh, which together account for 80 percent of all users. The prevalence of smokeless tobacco in these countries varies between 25 and 51 percent, and its use among youth is as high as cigarette smoking.
Effects of nicotine gum on blood vessels
While nicotine gum is a popular method of nicotine replacement therapy, it may not be safe to use during pregnancy. Its nicotine and its metabolite can pass into breast milk an hour after the mother quits smoking. This can have severe consequences on the infant, as nicotine increases its heart rate.
Nicotine can also cause high blood pressure and affect blood vessels in the body. It can also constrict tiny blood vessels in the mouth, limiting blood flow to the gums. This can be harmful because blood flow is vital for fighting bacteria in dental plaque and tartar.
Side effects of nicotine gum
Smoking is known to have numerous side effects. Nicotine gum is no exception. Smokers may experience nausea, heartburn, or even a rash. It is also difficult to use for people with dentures or other dental work. The right way to chew nicotine gum is essential for maximum effectiveness. Using it improperly can cause a variety of side effects, including excessive salivation, sore mouth, and hiccups. People who chew tobacco for long periods may develop obesity and diabetes. Furthermore, long-term chewers often experience chronic fatigue.
If you are pregnant, you should seek medical advice before using nicotine gum. You should also consult with a doctor if you smoke, as nicotine gum can cause a condition called leukoplakia in the mouth. Leukoplakia is a small gray or white patch in the mouth that can progress to cancer. These patches are usually painless but should be treated if you see any signs of early cancer.